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本帖最后由 tess1029 于 2014-10-6 10:16 编辑 * U Z( p" m4 L5 `6 D
& g0 h5 ]7 X% d2014年10月4日讯 /生物谷BIOON/ --日本读卖新闻最近刊登了一篇新闻称,中国科学界在干细胞研究领域发表的论文数已经超过了日本,而这一领域一直被认为是解决一些医学重大难题如神经退行性疾病药物研发的突破点。这也使得中国在该领域发表的论文总数量一跃升至第二位。目前在干细胞研究领域发表论文数最多的前三个国家依次是美国、中国和日本。据日本媒体报道,近年来中国在干细胞研究领域的各个方面都取得了长足的进步,这一进步也直接体现在发表论文数上,而反观日本学术界,近年来在该领域取得的成绩就显得乏善可陈,除了在人工诱导多能干细胞(iPS)领域占据优势以外,在其他干细胞研究领域的进步都十分缓慢。7 ^# L4 ^2 H- x% f5 k+ |9 H( s
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这一结论是日本媒体分析了2008年-2012年发表的超过17500篇干细胞领域相关论文后得出的,在这些研究中,来自美国研究机构的成果多达5129项,而中国和日本分别发表了1640和1350篇论文。而在2004年-2009年之间,日本的成果数则位居第二。5 `- A( |+ V* c a
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同时日本媒体还统计了在干细胞领域取得成绩最显着的前50家大学和研究机构。其中美国的研究机构几乎占据了这份榜单的半壁江山,而加州大学和斯坦福大学则分居冠亚军,傲视群雄。而日本则共有5家研究机构上榜,其中京都大学位居第六位、东京大学位居第十四位。而中国则有七家科研单位上榜,其中以位居第十一位的中山大学领跑。
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8 K% ]8 V' i# i X* h+ e一直以来,日本在iPS领域都享有盛名,2012年山中伸弥就因为在该领域出色的研究而与英国的约翰戈登分享了诺贝尔生理学奖。然而,最近因为小保方晴子等人在Nature上发表的研究成果涉嫌造假,也为日本的iPS乃至整个干细胞研究都蒙上了一层阴影。而事件的另一重要人物小保方晴子的导师,著名科学家笹井芳树的自杀也为这一事件蒙上了一层悲剧色彩。
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% ~$ Q0 q: N' F) e0 i* W; X) ^9 T5 W$ h不过,尽管近年来中国学术界在干细胞研究领域取得了一定的进展,但这却不是我们沾沾自喜的时候,一方面是我们距离前面的美国仍有很大距离,另一方面我们必须正视在这一领域,中国的科学家并没有多少重量级的研究成果。因此,在这一领域中,中国学术界仍然是任重道远。(生物谷Bioon.com)
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4 g7 b: I8 e" \& o) J详细英文报道:1 g: N9 R9 @$ a+ A4 W- r2 H# J
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Japan fell below China in the number of articles published on stem cells, which are expected to lead to the practical realization of regenerative medicine treatments and products, slipping from second to third place, according to a survey report by the Japan Patent Office.
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Amid increasingly fierce international competition in stem cell research, the United States, which tops the list, and China saw a steady increase in the number of articles in a wide range of research areas, while the number of articles in Japan grew at a sluggish pace in research areas other than induced pluripotent stem (iPS) cells, according to the report./ Q9 H# e2 C9 ?1 ^: \" q: [, Z
& o5 b) z1 d! Q$ [. S) U/ [The office analyzed about 17,500 articles related to stem cell research published from 2008 to 2012 by using a database of the U.S. National Library of Medicine, in which medical papers from around the world are registered. Concerning the nationalities of the institutions to which the lead authors of the articles belonged, the United States came in first place, as the lead authors of 5,129 articles belonged to U.S. institutions. China came in second by increasing its number from the previous period to 1,640, and Japan placed third with 1,350.1 i8 n0 m* M& y) h
9 V$ G& d( i* EIn the previous survey covering the period from 2004 to 2009, Japan came in second place, but in the latest survey, Japan was overtaken by China, which had placed fourth in the previous survey.' m! E, Z- N+ v8 w0 g
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By research institution, the University of California topped the list, followed by Stanford University, as institutions in the United States accounted for half of the top 50. For Japan, five research institutions were in the top 50, such as Kyoto University in sixth place and the University of Tokyo in 14th. However, Japan was outnumbered by China, as seven Chinese institutions were within the top 50, led by Sun Yat-sen University in 11th place.
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By area of research, the number of articles on iPS cells in Japan increased 11 times over the period from 2008 to 2012. But the number of articles on mesenchymal stem cells, which can develop into bones or cardiac muscles, increased from 1.4 times to 2.5 times in Europe, the United States and China, while the figure in Japan remained flat.
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