![Rank: 1](static/image/common/star_level1.gif)
- 积分
- 0
- 威望
- 0
- 包包
- 4
|
关于iPS的作用机制,这篇Nature Review Molecular Cell Biology的 Review是个不错的归纳:Open chromatin in pluripotency and reprogramming。作者提出了2个原则: specific factors maintain a globally) _1 Y) u3 C, S% I/ {3 P
open chromatin state that is accessible for transcriptional activation; and other chromatin( ?* `2 V+ Q+ g3 T! ~& @2 `
regulators contribute locally to the silencing of lineage-specific genes until differentiation is5 Y6 U- `; O8 B5 n
triggered. |
附件: 你需要登录才可以下载或查看附件。没有帐号?注册
-
总评分: 威望 + 5
包包 + 10
查看全部评分
|