求助nature Review一篇文章

woaipi

Nat Rev Mol Cell Biol. 2008 Jan;9(1):82-8.
3 w8 Y, F" z. a( HEpidermal homeostasis: do committed progenitors work while stem cells sleep?5 X9 V8 _$ i: |5 o  {/ f
Jones P, Simons BD.
5 x7 Y; u5 O  F" X3 y" |: P1 J% F( RSource
% D+ Z/ x$ x; U5 j. `, v; mPhilip Jones is at the MRC Cancer Cell Unit, Hutchison/MRC Research Centre, Cambridge, CB2 2XZ, UK. phj20@hutchison-mrc.cam.ac.uk
7 B! }3 O  M0 w4 ]  ^- L7 ~: `/ ^. x/ R
2 Y+ m2 Y% [9 R+ m2 GAbstract  }9 r4 l- m  h0 N. A& A
Tracking the fate of cells in murine epidermis in vivo has revealed that a committed progenitor cell population can maintain normal adult tissue in the long term without support from a long-lived, self-renewing population of stem cells. Here, we argue that these results challenge the dogma that stem-cell proliferation is required for the cellular homeostasis of the epidermis and other adult tissues, with important implications for tissue physiology and disease.9 O$ A7 V3 `( G# l5 }1 q

4 C5 q/ A: L' s' }7 [  dhttp://www.ncbi.nlm.nih.gov/pubmed?term=Epidermal%20homeostasis%3A%20do%20committed%20progenitors%20work%20while%20stem%20cells%20sleep%3F%20

woaipi

已经解决，来共享