求关于小分子在iPSCs诱导过程中的作用有关文献

genedu

各位大虾，谁手里有关于替代OCT4，SOX2，Klf4，c-Myc这四个因子以及其他诱导因子的小分子的文献？小弟拜谢了
! {/ d/ S; p( G0 G如果有哪位神人实际操作过的，请告知小分子名称及其用量。) e; n9 N# `6 Z, W+ S# ^1 p
再次拜谢

cellbuddies

可以参考丁盛的文章，给你一个文章列表
4 f- z$ y6 m. r4 M# p! OGeneration of Rat and Human Induced Pluripotent Stem Cells by Combining Genetic Reprogramming and Chemical Inhibitors5 N, x: [8 j3 B& e
Small molecules that modulate embryonic stem cell fate and somatic cell reprogramming+ Z; K! b: |  G3 C" P
A chemical platform for improved induction of human iPSCs-supplemental methods and data7 Y. Q- D% F6 \2 V3 |/ r! a7 P
还有University of Cambridge的Austin Smiths
' Q& h% u/ [9 UPromotion of Reprogramming to Ground State Pluripotency by Signal Inhibition

cellbuddies

full text

cellbuddies

MEK inhibitor PD0325901 (Sigma, 0.5 μM): s' s& [8 e9 H6 \/ k4 ~( n
ALK5 inhibitor A-83-01 (Tocris Bioscience, 0.5 μM)
9 s% p% c' p3 q; w3 i4 M& @GSK3β inhibitor CHIR99021 (BioVision, 3 μM)  j% ?, h/ o" A. y3 G
挺贵的，大概5000大洋

genedu

回复 cellbuddies 的帖子
! r6 W  I7 _6 S% n( j0 M7 U# e2 p. ~
真是太感谢了。临帖涕零，不知所言